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Differences F2 isoprostanes levels in male mice (Mus musculus L.) Maximum Physical Exercise Without Supplementation

Last modified: 2020-11-21


Strenuous physical exercise which exceeded the limit fatigue can increase the formation of free radicals that lead to oxidative stress. One of the biomarkers used to determine the presence of oxidative stress is F2-isoprostanes. The study aims to find out the difference F2-isoprostanes levels in male mice (Mus musculus L) by physical exercise maximum without supplementation. The population in the study was male mice weighing 30-35 grams aged 8-10 weeks and the sample was 30 male mice that met the criteria. Sampled blood plasma examination used the ELISA method and the data were processed in tables and graphs. The statistical test results obtained p value <0.05 (p <0.001), so there is a difference in the level of F2-isoprostanes between groups that are not and who are given maximum physical exercise. F2-isoprostanes levels given maximum physical exercise increased 2 times than those not given exercise


maximum physical exercise, F2-isoprostanes, supplementation