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Strategic innovation of implementing a self-sustaining energy production system utilizing a closed-loop model in corn milling industries is crucial for enhancing operational efficiency and sustainability. This study aims to determine the energy requirements, assess mass balance, and develop a self-sustaining energy production process within corn milling industries. The research methodology encompasses the design of an integrated system, the application of green technology, and the comprehensive evaluation of system performance. The closed-loop system demonstrates notable energy efficiency and sustainability in corn milling industries. The corn milling process involves transforming whole, husked, and cobbed corn into dried kernels, requiring energy inputs. The by-product of this process, corn cobs, emerges as a potential alternative energy source. The research focuses on primary inputs, such as husked and cobbed corn, with a production cycle basis of 5,000 kg and an associated potential waste of 35.57 kWh. Despite this energy potential, it falls short of meeting the production process's energy needs, which amount to 64 kWh. The findings suggest that the Corn Milling industry is not yet considered energy self-sufficient due to suboptimal utilization of by-products. However, the research provides valuable insights for advancing technology in corn milling production, emphasizing sustainability and energy efficiency. The application of the closed-loop model within the corn milling industry serves as inspiration for similar innovations across diverse agricultural and food sectors. In conclusion, this research contributes significantly to the development of sustainable and energy-efficient corn milling production technology. As industries seek innovative approaches to address energy challenges, the closed-loop model proves to be a promising avenue for enhancing operational efficiency and promoting sustainability in the corn milling sector and potentially in broader agricultural and food processing.